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Emerging concepts and challenges in implementing the exposome paradigm in allergic diseases and asthma: a Practall document
Author(s) -
Agache Ioana,
Miller Rachel,
Gern James E.,
Hellings Peter W.,
Jutel Marek,
Muraro Antonella,
Phipatanakul Wanda,
Quirce Santiago,
Peden David
Publication year - 2019
Publication title -
allergy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.363
H-Index - 173
eISSN - 1398-9995
pISSN - 0105-4538
DOI - 10.1111/all.13690
Subject(s) - exposome , asthma , medicine , allergy , clinical immunology , immunology , environmental health
Exposome research can improve the understanding of the mechanistic connections between exposures and health to help mitigate adverse health outcomes across the life span. The exposomic approach provides a risk profile instead of single predictors and thus is particularly applicable to allergic diseases and asthma. Under the PRACTALL collaboration between the European Academy of Allergy and Clinical Immunology ( EAACI ) and the American Academy of Allergy, Asthma, and Immunology ( AAAAI ), we evaluated the current concepts and the unmet needs on the role of the exposome in allergic diseases and asthma.