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Recent developments and highlights in mechanisms of allergic diseases: Microbiome
Author(s) -
Lunjani hlanhla,
Satitsuksanoa Pattraporn,
Lukasik Zuzanna,
Sokolowska Milena,
Eiwegger Thomas,
O'Mahony Liam
Publication year - 2018
Publication title -
allergy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.363
H-Index - 173
eISSN - 1398-9995
pISSN - 0105-4538
DOI - 10.1111/all.13634
Subject(s) - atopic dermatitis , microbiome , dysbiosis , allergy , asthma , food allergy , immunology , medicine , immune system , dermatology , gut flora , biology , bioinformatics
All body surfaces are exposed to a wide variety of microbes, which significantly influence immune reactivity within the host. This review provides an update on some of the critical novel findings that have been published on the influence of the microbiome on atopic dermatitis, food allergy and asthma. Microbial dysbiosis has consistently been observed in the skin, gut and lungs of patients with atopic dermatitis, food allergy and asthma, respectively, and the role of specific microbes in allergic disorders is being intensively investigated. However, many of these discoveries have yet to be translated into routine clinical practice.