Is chronic rhinosinusitis related to allergic rhinitis in adults and children? Applying epidemiological guidelines for causation
Author(s) -
Christos Georgalas,
Ioannis Vlastos,
Valerie A. Picavet,
Cornelis M. van Drunen,
George Garas,
Emmanuel P. Prokopakis
Publication year - 2014
Publication title -
allergy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.363
H-Index - 173
eISSN - 1398-9995
pISSN - 0105-4538
DOI - 10.1111/all.12413
Subject(s) - causation , medicine , chronic rhinosinusitis , observational study , allergy , epidemiology , asthma , sinusitis , dermatology , intensive care medicine , pediatrics , immunology , pathology , political science , law
The relationship between allergic rhinitis and chronic rhinosinusitis has been assessed in a number of observational and experimental studies. In this review, we attempt their synthesis and evaluation using the modified Bradford Hill guidelines for causation. Although there is no proof of causation, especially in the pediatric literature, an evaluation of underlying allergies is recommended at least as an initial measure of symptoms relief.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom