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Relationship between asthma and cognition: the Cooper Center Longitudinal Study
Author(s) -
CalderaAlvarado G.,
Khan D. A.,
DeFina L. F.,
Pieper A.,
Brown E. S.
Publication year - 2013
Publication title -
allergy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.363
H-Index - 173
eISSN - 1398-9995
pISSN - 0105-4538
DOI - 10.1111/all.12125
Subject(s) - asthma , cognition , logistic regression , medicine , montreal cognitive assessment , cognitive test , cross sectional study , cognitive impairment , effects of sleep deprivation on cognitive performance , gerontology , clinical psychology , psychiatry , pathology
Background Minimal data are available on the relationship between asthma and cognitive performance. In this report, we examine the relationship between asthma and cognitive performance in older adults, a subpopulation with elevated risk of cognitive impairment. Methods We conducted a cross‐sectional, retrospective analysis of 1380 participants age ≥55 who completed preventive health examinations at the Cooper Clinic in Dallas, TX . Cognition was assessed using the Montreal Cognitive Assessment (Mo CA ), a brief test for mild cognitive impairment. Data were analyzed in a multiple logistic regression using Mo CA scores suggestive of cognitive impairment as the dependent variable. Results When controlling for demographic characteristics, self‐rated health status, inhaled corticosteroid use, and FEV 1 / FVC , asthma were associated with 78% increased risk of cognitive impairment ( P = 0.02) as defined by Mo CA score. Conclusions In the largest sample examined to date, we have identified a significant relationship between asthma and cognitive impairment in older people.