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Outcomes of status 1 liver transplantation for Budd‐Chiari Syndrome with fulminant hepatic failure
Author(s) -
Alukal Joseph J.,
Zhang Talan,
Thuluvath Paul J.
Publication year - 2021
Publication title -
american journal of transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.89
H-Index - 188
eISSN - 1600-6143
pISSN - 1600-6135
DOI - 10.1111/ajt.16410
Subject(s) - medicine , fulminant hepatic failure , liver transplantation , proportional hazards model , transplantation , budd–chiari syndrome , inferior vena cava
There is a paucity of data on the outcome of liver transplantation (LT) in Budd‐Chiari Syndrome (BCS) patients who are listed as status 1. The objective of our study was to determine patient or graft survival following LT in status 1 BCS patients. We utilized United Network for Organ Sharing (UNOS) database to identify all adult patients (> 18 years of age) listed as status 1 with a primary diagnosis of BCS in the United States from 1998 to 2018, and analyzed their outcomes and compared it to non‐status 1 BCS patients. Four hundred and forty‐six patients with BCS underwent LT between 1998 and 2018, and of these 55 (12.3%) were listed as status 1. There was no difference in long‐term post‐liver transplant or “intention‐to‐treat” survival from the time of listing to death or the last day of follow‐up between status 1 and non‐status 1 groups. Graft and patient survival at 5 years for status 1 patients were 75% and 82%, respectively. Cox regression analysis showed that patients listed as status 1 (aHR: 0.45, p < .02) were associated with a better survival. BCS patients listed as status 1 have excellent survival following emergency LT.