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Taking AIM2 at regulatory T cells to modulate autoimmune diseases
Author(s) -
Li Xian C.
Publication year - 2021
Publication title -
american journal of transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.89
H-Index - 188
eISSN - 1600-6143
pISSN - 1600-6135
DOI - 10.1111/ajt.16036
Subject(s) - aim2 , inflammasome , foxp3 , immunology , immune tolerance , immune system , pyroptosis , caspase 1 , inflammation , medicine , autoimmunity , microbiology and biotechnology , cancer research , biology
AIM2 safeguards Treg stability by suppressing the Akt‐mTOR pathway via the protein phosphatase PP2A.