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Novel coronavirus (SARS‐CoV‐2) infection in a renal transplant recipient: Case report
Author(s) -
Ning Ling,
Liu Lei,
Li Wenyuan,
Liu Hongtao,
Wang Jizhou,
Yao Ziqin,
Zhang Shengyu,
Zhao Desheng,
Nashan Björn,
Shen Aizong,
Liu Lianxin,
Li Lei
Publication year - 2020
Publication title -
american journal of transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.89
H-Index - 188
eISSN - 1600-6143
pISSN - 1600-6135
DOI - 10.1111/ajt.15897
Subject(s) - medicine , covid-19 , coronavirus , renal transplant , betacoronavirus , virology , coronavirus infections , pandemic , immunology , intensive care medicine , transplantation , infectious disease (medical specialty) , pathology , disease , outbreak
An ongoing outbreak of pneumonia associated with the severe acute respiratory coronavirus 2 (SARS‐CoV‐2) started in Wuhan, China, with cases now confirmed in multiple countries. The clinical course of patients remains to be fully characterized, clinical presentation ranges from asymptomatic infection to acute respiratory distress syndrome and acute renal failure, and no pharmacological therapies of proven efficacy yet exist. We report a case of SARS‐CoV‐2 infection in a renal transplant recipient with excellent outcome. This case states the importance of close monitoring of the concentration of cyclosporine in patients treated with lopinavir/ritonavir; the routine treatment of corticosteroid can be continued. This is a rare report of SARS‐CoV‐2 infection in a renal transplant recipient. Further data are needed to achieve better understanding of the impact of immunosuppressive therapy on the clinical presentation, severity, and outcome of SARS‐CoV‐2 infections in solid organ transplant recipients.