American Journal of Transplantation: Volume 20, Number 3, March 2020

On the cover: Islet transplantation remains a promising means of beta cell replacement, but islet allo‐ and xenograft immune destruction remains a significant problem. This month, in a robust nonhuman primate islet allotransplant model, Stabler et al ( page 689) demonstrate that grafting polyethylene glycol (PEG) polymer chains onto islets markedly improves their function and survival in vivo. This relatively simple ex vivo modification could provide a new means of lessening the need for immunosuppression following islet transplantation. Cover design by Megan Llewellyn, Duke University Department of Surgery.