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American Journal of Transplantation: Volume 20, Number 3, March 2020
Publication year - 2020
Publication title -
american journal of transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.89
H-Index - 188
eISSN - 1600-6143
pISSN - 1600-6135
DOI - 10.1111/ajt.15802
Subject(s) - medicine , transplantation , volume (thermodynamics) , quantum mechanics , physics
On the cover: Islet transplantation remains a promising means of beta cell replacement, but islet allo‐ and xenograft immune destruction remains a significant problem. This month, in a robust nonhuman primate islet allotransplant model, Stabler et al ( page 689) demonstrate that grafting polyethylene glycol (PEG) polymer chains onto islets markedly improves their function and survival in vivo. This relatively simple ex vivo modification could provide a new means of lessening the need for immunosuppression following islet transplantation. Cover design by Megan Llewellyn, Duke University Department of Surgery.