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Report from the American Society of Transplantation on frailty in solid organ transplantation
Author(s) -
Kobashigawa Jon,
Dadhania Darshana,
Bhorade Sangeeta,
Adey Deborah,
Berger Joseph,
Bhat Geetha,
Budev Marie,
DuarteRojo Andres,
Dunn Michael,
Hall Shelley,
Harhay Meera N.,
Johansen Kirsten L.,
Joseph Susan,
Kennedy Cassie C.,
Kransdorf Evan,
Lentine Krista L.,
Lynch Raymond J.,
McAdamsDeMarco Mara,
Nagai Shunji,
Olymbios Michael,
Patel Jignesh,
Pinney Sean,
Schaenman Joanna,
Segev Dorry L.,
Shah Palak,
Singer Lianne G.,
Singer Jonathan P.,
Sonnenday Christopher,
Tandon Puneeta,
Tapper Elliot,
Tullius Stefan G.,
Wilson Michael,
Zamora Martin,
Lai Jennifer C.
Publication year - 2019
Publication title -
american journal of transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.89
H-Index - 188
eISSN - 1600-6143
pISSN - 1600-6135
DOI - 10.1111/ajt.15198
Subject(s) - medicine , transplantation , organ transplantation , intensive care medicine , gerontology , psychological intervention , nephrology , frailty syndrome , kidney transplantation , frailty index , psychiatry
A consensus conference on frailty in kidney, liver, heart, and lung transplantation sponsored by the American Society of Transplantation (AST) and endorsed by the American Society of Nephrology (ASN), the American Society of Transplant Surgeons (ASTS), and the Canadian Society of Transplantation (CST) took place on February 11, 2018 in Phoenix, Arizona. Input from the transplant community through scheduled conference calls enabled wide discussion of current concepts in frailty, exploration of best practices for frailty risk assessment of transplant candidates and for management after transplant, and development of ideas for future research. A current understanding of frailty was compiled by each of the solid organ groups and is presented in this paper. Frailty is a common entity in patients with end‐stage organ disease who are awaiting organ transplantation, and affects mortality on the waitlist and in the posttransplant period. The optimal methods by which frailty should be measured in each organ group are yet to be determined, but studies are underway. Interventions to reverse frailty vary among organ groups and appear promising. This conference achieved its intent to highlight the importance of frailty in organ transplantation and to plant the seeds for further discussion and research in this field.