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Transplantation of pediatric renal allografts from donors less than 10 kg
Author(s) -
Mitrou Nicholas,
Aquil Shahid,
Dion Marie,
McAlister Vivian,
Sener Alp,
Luke Patrick P.
Publication year - 2018
Publication title -
american journal of transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.89
H-Index - 188
eISSN - 1600-6143
pISSN - 1600-6135
DOI - 10.1111/ajt.14946
Subject(s) - medicine , transplantation , creatinine , surgery , complication , renal transplant , thrombosis , body weight , urology
Few transplant programs use kidneys from donors with body weight ( BW ) < 10 kg. We hypothesized that pediatric en bloc transplants from donors with BW < 10 kg would provide similar transplant outcomes to larger grafts. All pediatric en bloc renal transplants performed at our center between 2001 and 2017 were reviewed (N = 28). Data were stratified by smaller (donor BW < 10 kg; n = 11) or larger donors ( BW > 10 kg; n = 17). Renal volume was assessed during follow‐up with ultrasound. Demographic characteristics were similar between the 2 groups of recipients. After mean follow‐up of 44 months (smaller donors) and 124 months (larger donors), graft and patient outcomes were similar between groups. Serum creatinine at 1, 3, and 5 years was no different between groups. At 1 day posttransplant, mean total renal volume in the smaller donors was 28 ± 9 mm 3 vs 45 ± 12 mm 3 ( P < .01). By 3 weeks, it was 53 ± 19 mm 3 (smaller donors) versus 73 ± 19 mm 3 (larger donors) ( P = NS ). Complication rates were similar between both groups with 1 case of venous thrombosis in the smaller group. With experience, outcomes are equivalent to those from larger pediatric donors.