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Mind the GAP , for Tolerance to Gut Bacteria
Author(s) -
Alegre MariaLuisa
Publication year - 2018
Publication title -
american journal of transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.89
H-Index - 188
eISSN - 1600-6143
pISSN - 1600-6135
DOI - 10.1111/ajt.14682
Subject(s) - medicine , bacteria , gut bacteria , gut flora , intensive care medicine , immunology , biology , genetics
Precise spatial and temporal immune sensing of gut microbiota in the postnatal and weaning period, via intestinal GAPs, is essential for immune tolerance to gut commensals and subsequent resistance to inflammatory bowel disease.