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Stealing Tregs’ Identity (by Deleting NF ‐κB)
Author(s) -
Alegre MariaLuisa
Publication year - 2017
Publication title -
american journal of transplantation
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 2.89
H-Index - 188
eISSN - 1600-6143
pISSN - 1600-6135
DOI - 10.1111/ajt.14554
Subject(s) - transcription factor , foxp3 , peripheral tolerance , microbiology and biotechnology , chromatin , t cell , biology , regulatory t cell , effector , immunology , immune system , cancer research , il 2 receptor , genetics , gene
The same transcription factor NF‐κB enables the opposing effects of Tconv activation and Treg maintenance/suppression by accessing different areas of open chromatin in each cell type.
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