Premium
Cytomegalovirus‐Induced Polyarteritis Nodosa in a Liver Transplant Recipient
Author(s) -
Abadeer K.,
Aslam N.,
Cortese C.,
Wadei H. M.
Publication year - 2017
Publication title -
american journal of transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.89
H-Index - 188
eISSN - 1600-6143
pISSN - 1600-6135
DOI - 10.1111/ajt.14376
Subject(s) - polyarteritis nodosa , medicine , cytomegalovirus , vasculitis , necrotizing vasculitis , kidney , urinary system , virus , immunology , pathology , virology , herpesviridae , viral disease , disease
Polyarteritis nodosa ( PAN ) is a necrotizing vasculitis that has been associated with viral infections, especially hepatitis B virus. We hereby report a case of tissue‐invasive cytomegalovirus ( CMV )‐induced PAN in a liver transplant recipient presenting with acute kidney injury and active urinary sediment. Treatment directed against both PAN and CMV resulted in improvement in kidney function, normalization of urinary indices and resolution of the CMV infection. There was no recurrence of either PAN or CMV after a 3‐year follow‐up period.