American Journal of Transplantation: Volume 17, Number 3, March 2017

On the cover this month: Transplantation's considerable benefit is tempered by a continued requirement for nonspecific T cell–directed immunosuppression, and with it, impaired protective immunity, particularly against viral pathogens. This month we highlight articles covering the breadth of viral disease in transplantation, including well‐known pathogens such as Epstein–Barr virus (Dharnidharka, page 611; AlDabbagh et al, page 770), cytomegalovirus (Zheng et al, page 657), and BK virus (Kuppachi et al, page 813), as well as less common pathogens such as West Nile virus (Wilson et al, page 803) and parainfluenza virus (Helanterä et al, page 809). We also feature a recent commentary on an emerging threat, Zika virus (Nogueira et al, page 791, and Blumberg and Fishman's editorial on page 599). These articles continue to underscore the immune consequences of organ transplantation, and impel continued work toward more precise immune management strategies. Cover design by Scott Behm and Deanna Hoskins, Duke University Department of Surgery .