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The Novel Application of Genomic Profiling Assays to Shorten Inactive Status for Potential Kidney Transplant Recipients With Breast Cancer
Author(s) -
Mukhtar R. A.,
Piper M. L.,
Freise C.,
Van't Veer L. J.,
Baehner F. L.,
Esserman L. J.
Publication year - 2017
Publication title -
american journal of transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.89
H-Index - 188
eISSN - 1600-6143
pISSN - 1600-6135
DOI - 10.1111/ajt.14003
Subject(s) - medicine , breast cancer , profiling (computer programming) , kidney transplant , oncology , computational biology , kidney transplantation , cancer research , kidney , cancer , biology , computer science , operating system
The concern about cancer recurrence has traditionally resulted in delaying kidney transplantation for 2–5 years after a cancer diagnosis in patients who are otherwise eligible for transplant. This period of inactive status to observe the tumor biology can result in significant morbidity and decreased quality of life for patients with end‐stage renal disease ( ESRD ). We reported the novel application of genomic profiling assays in breast cancer to identify low‐risk cancers in two patients with ESRD who were able to have the mandatory inactive status eliminated prior to kidney transplantation.