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Steroid‐Responsive Acute Rejection Should Not Be the End Point for Immunosuppressive Trials
Author(s) -
Klintmalm G. B.,
Vincenti F.,
Kirk A.
Publication year - 2016
Publication title -
american journal of transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.89
H-Index - 188
eISSN - 1600-6143
pISSN - 1600-6135
DOI - 10.1111/ajt.13889
Subject(s) - medicine , calcineurin , nephrotoxicity , immunosuppression , surgery , septic shock , transplantation , kidney , sepsis
Development of new immunosuppressive regimens for transplantation has come to a standstill, leading the authors to urge for substantial change of the current regulatory requirements and endpoints for new agent approval.