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Regulating T Cell Behavior
Author(s) -
Knechtle S. J.,
Fairchild R. L.
Publication year - 2016
Publication title -
american journal of transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.89
H-Index - 188
eISSN - 1600-6143
pISSN - 1600-6135
DOI - 10.1111/ajt.13724
Subject(s) - foxp3 , medicine , immunology , immune system , immunotherapy , transplant rejection , disease , autoimmune disease , t cell , transplantation , in vitro , in vivo , biology , antibody , biochemistry , microbiology and biotechnology
Regulatory T cells propagated in vitro and administered to transplant patients in vivo to prevent rejection may be influenced by complex factors as yet poorly understood, and a well‐presented study challenges their ability to prevent rejection in nonhuman primates. See Ezzelarab et al's article on page 1999.