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Therapeutics for A ntibody‐Mediated Rejection : A Slippery Slope Into Confusion
Author(s) -
Montgomery R. A.
Publication year - 2016
Publication title -
american journal of transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.89
H-Index - 188
eISSN - 1600-6143
pISSN - 1600-6135
DOI - 10.1111/ajt.13721
Subject(s) - medicine , antibody , transplantation , confusion , immunology , plasmapheresis , glomerulopathy , kidney , proteinuria , surgery , psychology , psychoanalysis
In this editorial, the author expresses concerns that poorly designed studies fail to answer important questions about the safety and efficacy of new drugs for the treatment of antibody‐mediated rejection but can result in rapid acceptance and off‐label use in transplantation based solely on a pilot study and promising mechanisms of action. See Viglietti et al's article on page 1596.