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Developing New Immunosuppression for the Next Generation of Transplant Recipients: The Path Forward
Author(s) -
Stegall M. D.,
Morris R. E.,
Alloway R. R.,
Man R. B.
Publication year - 2016
Publication title -
american journal of transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.89
H-Index - 188
eISSN - 1600-6143
pISSN - 1600-6135
DOI - 10.1111/ajt.13582
Subject(s) - medicine , immunosuppression , intensive care medicine , drug development , immunology , drug , pharmacology
The development of new immunosuppressive drugs has slowed markedly over the past several years, and the outlook that improved therapy will be available to the next generation of transplant recipients is bleak. In this viewpoint, the authors outline some of important barriers to new drug development and suggest specific steps that the transplant community can take to overcome them.