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Do Mice Need an Order of Fries to Be Relevant for Transplant Studies?
Author(s) -
Sawinski D.,
Maltzman J. S.
Publication year - 2015
Publication title -
american journal of transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.89
H-Index - 188
eISSN - 1600-6143
pISSN - 1600-6135
DOI - 10.1111/ajt.13348
Subject(s) - medicine , function (biology) , order (exchange) , hyperlipidemia , immunology , microbiology and biotechnology , biology , endocrinology , diabetes mellitus , finance , economics
This editorial emphasizes the breadth of factors in mouse models through commentary on two articles demonstrating that genetically or environmentally induced hyperlipidemia promotes allograft rejection through alterations of both Th17 and Treg cell function. See Bagley et al (page 2324 ) and Yuan et al (page 2336 ).