Renal Autotransplantation in Lynch Syndrome: A Viable Option in a Patient With Contralateral Metachronous Ureteral Cancer | Zendy

Woods T. | Zendy; Jennings N. B. | Zendy; Fernandez H. T. | Zendy; Onaca N. | Zendy; Carlile B. K. | Zendy; Levy M. F. | Zendy; Gould D. L. | Zendy; Ruiz R. | Zendy

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Renal Autotransplantation in Lynch Syndrome: A Viable Option in a Patient With Contralateral Metachronous Ureteral Cancer

Author(s) -

Woods T.,

Jennings N. B.,

Fernandez H. T.,

Onaca N.,

Carlile B. K.,

Levy M. F.,

Gould D. L.,

Ruiz R.

Publication year - 2015

Publication title -

american journal of transplantation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.89

H-Index - 188

eISSN - 1600-6143

pISSN - 1600-6135

DOI - 10.1111/ajt.13279

Subject(s) - medicine , allotransplantation , autotransplantation , surgery , transplantation , kidney transplantation , kidney , kidney disease , cancer , renal function , urology

The success of human kidney allotransplantation was realized over six decades ago. First described 50 years ago, renal auto transplantation has been utilized sparingly as a salvage procedure for patients at risk of losing renal function, either from a benign or malignant condition. While classically associated with colorectal malignancies, Lynch syndrome also carries a small yet significant risk for the development of ureteral carcinoma. For these patients who develop chronic kidney disease, allotransplantation may not be an option due to the lifelong risk of several malignancies. We report the first known case of renal autotransplantation in a patient with metachronous ureteral cancer due to Lynch syndrome.

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