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American Journal of Transplantation: Volume 14, Number 5, May 2014
Publication year - 2014
Publication title -
american journal of transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.89
H-Index - 188
eISSN - 1600-6143
pISSN - 1600-6135
DOI - 10.1111/ajt.12775
Subject(s) - medicine , transplantation , volume (thermodynamics) , intensive care medicine , quantum mechanics , physics
On the cover this month: Hepatitis C virus (HCV) remains one of the most common indications for liver transplantation and a significant problem for much of the chronic dialysis population. Importantly, although liver transplantation is an effective remedy for HCV‐related liver failure, posttransplant HCV recurrence remains a near certainty. However, many new antiviral agents are emerging with legitimate promise to not only control HCV, but eliminate it. Gane and Agarwal (page 994 ) provide an update on the drugs that may potentially dethrone HCV as a top indication for transplantation. Also in this issue, Stock et al (page 1136 ) make novel observations regarding an association between sirolimus exposure and a lower frequency of CD4 lymphocytes containing HIV DNA, suggesting that immunosuppression required for kidney transplantation in the HIVinfected recipient may impact the level of HIV persistence. Cover design by Ken North, North Design Group.