Cryptococcosis in Solid Organ Transplantation | Zendy

Baddley J. W. | Zendy; Forrest G. N. | Zendy

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Cryptococcosis in Solid Organ Transplantation

Author(s) -

Baddley J. W.,

Forrest G. N.

Publication year - 2013

Publication title -

american journal of transplantation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.89

H-Index - 188

eISSN - 1600-6143

pISSN - 1600-6135

DOI - 10.1111/ajt.12116

Subject(s) - cryptococcosis , medicine , incidence (geometry) , hematopoietic stem cell transplantation , transplantation , scopus , organ transplantation , fluconazole , immunology , medline , antifungal , biology , dermatology , biochemistry , physics , optics

Cryptococcosis is the third most commonly occurring invasive fungal infection in solid organ transplant (SOT) recipients. Approximately 8% of invasive fungal infections in SOT recipients are due to cryptococcosis (1). The overall incidence of cryptococcosis in SOT recipients ranges from 0.2% to 5% (1,2). Cryptococcosis is typically a late-occurring infection; the median time to onset usually ranges from 16 to 21 months posttransplantation (1,3,4). The time to onset is earlier for liver and lung (<12 months) compared to kidney transplant recipients and this may be due to a higher intensity of immunosuppression in the former subgroups (4).

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