Premium
Clostridium difficile Infections in Solid Organ Transplantation
Author(s) -
Dubberke E. R.,
Burdette S. D.
Publication year - 2013
Publication title -
american journal of transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.89
H-Index - 188
eISSN - 1600-6143
pISSN - 1600-6135
DOI - 10.1111/ajt.12097
Subject(s) - medicine , clostridium difficile , solid organ , transplantation , organ transplantation , microbiology and biotechnology , intensive care medicine , antibiotics , biology
Clostridium difficile infection (CDI) is a commonproblem encounteredin solid-organ transplant (SOT) recipients and the incidence is increasing. SOT recipients have an incidence of CDI that is higher than other postoperative patients, and this group has several unique risk factors that may contribute to more severe disease. Recent publications in nontransplant patients have indicated that treatment choices should be based on the severity of the illness (1). Although there continues to be a lack of well-designed, randomized, controlled trials to support the management decisions that must be made for SOT recipients with CDI, the available evidence is reviewed and summarized for these treatment guidelines.