Premium
Acute fatty liver of pregnancy – A short review
Author(s) -
Donck Marie,
Vercruysse Yoann,
Alexis Alexandros,
Rozenberg Serge,
Blaiberg Samantha
Publication year - 2021
Publication title -
australian and new zealand journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.734
H-Index - 65
eISSN - 1479-828X
pISSN - 0004-8666
DOI - 10.1111/ajo.13293
Subject(s) - acute fatty liver of pregnancy , caesarean section , pregnancy , medicine , amplified fragment length polymorphism , fetus , perinatal mortality , obstetrics , fatty liver , biology , environmental health , population , genetics , disease , genetic diversity
Acute fatty liver of pregnancy (AFLP) is a rare but dramatic condition associated with a high maternal and fetal morbidity and mortality. We present a short review of AFLP management, illustrated by a case report. We conducted a systematic literature search for ‘acute fatty liver of pregnancy’, concerning its management. We found initially 11 studies, and three of them met the selection criteria. Prompt diagnosis, maternal stabilisation and rapid delivery are mandatory. This illustrative AFLP case fulfilled nine out of 14 Swansea criteria. Caesarean section is often required (as illustrated in this case), reducing maternal and perinatal mortality rates.