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Exercise in pregnancy does not alter gestational weight gain, MCP ‐1 or leptin in obese women
Author(s) -
Dekker Nitert Marloes,
Barrett Helen L.,
Denny Kerina J.,
McIntyre H. David,
Callaway Leonie K.
Publication year - 2015
Publication title -
australian and new zealand journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.734
H-Index - 65
eISSN - 1479-828X
pISSN - 0004-8666
DOI - 10.1111/ajo.12300
Subject(s) - medicine , leptin , weight gain , gestation , pregnancy , birth weight , endocrinology , cord blood , obstetrics , physical therapy , obesity , body weight , biology , genetics
Background Increasing physical activity in pregnancy may improve pregnancy outcomes for obese women. Exercise could reduce gestational weight gain, improve the maternal circulating lipid profile as well as alter leptin, Interleukin‐8 (IL‐8) and Monocyte Chemoattractant Protein‐1 (MCP‐1) levels. Aim The aim of this study was to investigate the effects of exercise on gestational weight gain, maternal circulating lipids, IL ‐8, MCP ‐1 and leptin levels in obese pregnant women. Materials and Methods The analysis was performed in the 35 obese women enrolled in the pilot BAMBINO randomised controlled trial who provided blood samples at 12‐ and 28‐weeks gestation. Women in the exercise intervention arm received an individualised exercise plan. Blood samples, exercise diary and pedometer data were obtained at 12‐, 20‐, 28‐ and 36‐weeks' gestation. Cord blood was obtained at delivery. Results Women in the exercise arm exercised more than those in the control arm ( P = 0.038). There was no difference in gestational weight gain, excess gestational weight gain, MCP‐1 and leptin levels between women in the exercise intervention ( n = 19) or the control arm ( n = 16). IL‐8 was not detectable. Exercise did not alter the maternal lipid profile. Conclusions The low level of physical activity achieved in obese women in the exercise intervention arm was insufficient to alter gestational weight gain, MCP ‐1, leptin or circulating lipid levels.