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Prospective audit of vitamin D levels of women presenting for their first antenatal visit at a tertiary centre
Author(s) -
De Laine Kate M.,
Matthews Geoff,
Grivell Rosalie M.
Publication year - 2013
Publication title -
australian and new zealand journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.734
H-Index - 65
eISSN - 1479-828X
pISSN - 0004-8666
DOI - 10.1111/ajo.12052
Subject(s) - medicine , guideline , vitamin d and neurology , pregnancy , vitamin d deficiency , obstetrics , pediatrics , body mass index , prospective cohort study , caesarean section , vitamin , gynecology , genetics , pathology , biology
Background Vitamin D deficiency in pregnancy is associated with adverse events such as pre‐eclampsia, primary caesarean section and vitamin D deficiency of the newborn. Vitamin D screening in pregnancy is not universal. Aims To evaluate the vitamin D status of pregnant women at our institution and assess the sensitivity of the current risk‐based screening guideline. Methods A prospective audit of vitamin D levels of all women presenting for their first antenatal booking visit during 3 four‐week periods (in 2009–2010) was conducted at the W omen's and C hildren's H ospital, S outh A ustralia. The main outcome measure was 25‐hydroxyvitamin D 3 levels. Information was also collected on body mass index, self‐reported ethnicity and whether or not vitamin D testing was indicated based on the hospital guidelines. Results Four hundred and seventy‐two women consented to inclusion in the audit. 67.4% (318/472) were ‘low‐risk’ according to the hospital guidelines for vitamin D screening. 46.2% of these women and 78.6% of ‘high‐risk’ women were vitamin D deficient (<60 nmol/L). Mean vitamin D levels were 62.7 ± 22.0 and 43.4 ± 26.3 nmol/L for low‐ and high‐risk women, respectively. 54.9% (147/268) of women who were found to be vitamin D deficient were classified as ‘low‐risk’ giving a sensitivity of 45% for the current risk‐based screening guideline. Conclusions Based on current normal ranges for vitamin D, risk‐based screening criteria for vitamin D deficiency in pregnancy fails to detect over half of vitamin D deficient women at our institution. Current S outh A ustralian guidelines should be amended in favour of universal screening of vitamin D for all pregnant patients at their booking visit.