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A prospective longitudinal study on rotation thromboelastometry in women with uncomplicated pregnancies and postpartum
Author(s) -
RheenenFlach Leonie E.,
Zweegman Sonja,
Boersma Fleur,
Lenglet Joris E.,
Twisk Jos W. R.,
Bolte Antoinette C.
Publication year - 2013
Publication title -
australian and new zealand journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.734
H-Index - 65
eISSN - 1479-828X
pISSN - 0004-8666
DOI - 10.1111/ajo.12023
Subject(s) - thromboelastometry , obstetrics , medicine , longitudinal study , prospective cohort study , rotation (mathematics) , surgery , mathematics , geometry , pathology , whole blood
Background Rotation thromboelastometry ( ROTEM ) is an easy, fast and complete method of measuring coagulation. Aims Our goal was to obtain longitudinal values on ROTEM in uncomplicated pregnancies and in the puerperium. Materials and Methods Healthy women, who visited our outpatient clinic for antenatal checks and who accomplished an uncomplicated pregnancy were tested three times during pregnancy and one time postpartum. Intrinsic and extrinsic pathway tests were carried out. Results In total, 62 women were analysed, and 298 measurements were taken. With increasing gestational age, there are significant changes towards hypercoagulability. Conclusion This study provides a better knowledge about physiological changes in ROTEM measurements during pregnancy. These normative data may serve as assistance for future studies and interventions.