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COVID‐19 and hydatidiform mole
Author(s) -
Abbas Ahmed M.,
Ahmed Lobna,
Salem Amera S.,
Elsamman Shimaa H.,
Refai Alshaima,
Fathy Safaa K.,
Ahmed Omar A.,
Shalotut Asmaa S.,
AbdelWahab Radwa A.
Publication year - 2020
Publication title -
american journal of reproductive immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.071
H-Index - 97
eISSN - 1600-0897
pISSN - 1046-7408
DOI - 10.1111/aji.13310
Subject(s) - pyrin domain , pregnancy , covid-19 , pathogenesis , pandemic , preeclampsia , immunology , disease , medicine , biology , inflammasome , inflammation , genetics , infectious disease (medical specialty)
The emergence of coronavirus disease 2019 (COVID‐19) as a pandemic threatens the entire world resulting in severe consequences for people's health. Pregnant patients with COVID‐19 had immune dysregulation that could result in abnormal pregnancy outcomes such as hydatidiform mole (HM), recurrent pregnancy loss, and early‐onset preeclampsia. In this article, we tried to summarize the possible association between COVID‐19 and the HM's development by reviewing the role of NOD‐Like Receptor (NLR) Family Pyrin Domain Containing 7 (NLRP7), cytokines, zinc, and leukocytes in the pathogenesis of HM.