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Peach gum polysaccharides improve the spermatogenesis of KKA y mice with impaired reproduction system
Author(s) -
Qian Li,
Wang Wenjun,
Song Jie,
Chen Dezhong
Publication year - 2017
Publication title -
american journal of reproductive immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.071
H-Index - 97
eISSN - 1600-0897
pISSN - 1046-7408
DOI - 10.1111/aji.12627
Subject(s) - spermatogenesis , triglyceride , reproduction , sperm , superoxide dismutase , antioxidant , medicine , endocrinology , biology , andrology , cholesterol , oxidative stress , ecology , biochemistry
Problem Peach gum polysaccharides ( PGP s) exhibit antioxidant and antibacterial activities. Nevertheless, the effect of PGP s on the spermatogenesis of KKA y mice with impaired reproduction system remains undetermined. Method of study PGP s were extracted with hot water. KKA y mice were randomly divided into two groups, namely, control and PGP s (treated with 100 mg/kg PGP s). Results Oral administration of PGP s decreased the levels of serum triglyceride, total cholesterol, low‐density lipoprotein cholesterol, fasting blood glucose, plasma insulin, and nitrate nitrogen level in the testes of KKA y mice. Moreover, treatment with PGP s increased the sperm density, sperm movement, rate of normal sperm morphology, protein expression level, and superoxide dismutase activity. Conclusion PGP s can effectively protect the spermatogenesis of KKA y mice with impaired reproduction system.