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Chronic Endometritis: Potential Cause of Infertility and Obstetric and Neonatal Complications
Author(s) -
Kitaya Kotaro,
Matsubayashi Hidehiko,
Yamaguchi Kohei,
Nishiyama Rie,
Takaya Yukiko,
Ishikawa Tomomoto,
Yasuo Tadahiro,
Yamada Hisao
Publication year - 2016
Publication title -
american journal of reproductive immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.071
H-Index - 97
eISSN - 1600-0897
pISSN - 1046-7408
DOI - 10.1111/aji.12438
Subject(s) - endometritis , infertility , etiology , medicine , pathogenesis , epidemiology , gynecology , obstetrics , disease , pelvic inflammatory disease , pregnancy , pathology , biology , genetics
Chronic endometritis ( CE ) is a local inflammatory disease characterized by unusual plasmacyte infiltration in the endometrial stromal areas. CE has been neglected in gynecologic practice, as it is a less symptomatic benign disease that requires demanding and time‐consuming histopathologic examinations for the definite diagnosis. Recent studies, however, suggest the association of CE with infertility and obstetric and neonatal complications. In this review article, we aimed to update the knowledge on epidemiology, etiology, and pathogenesis of CE as well as discuss its clinical management from diagnosis to treatment.