Premium
Understanding the Complexity of the Immune System during Pregnancy
Author(s) -
Racicot Karen,
Kwon JaYoung,
Aldo Paulomi,
Silasi Michelle,
Mor Gil
Publication year - 2014
Publication title -
american journal of reproductive immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.071
H-Index - 97
eISSN - 1600-0897
pISSN - 1046-7408
DOI - 10.1111/aji.12289
Subject(s) - pregnancy , immune system , context (archaeology) , fetus , immunology , immunity , obstetrics , medicine , affect (linguistics) , biology , psychology , communication , paleontology , genetics
Progress in our understanding of the role of the maternal immune system during healthy pregnancy will help us better understand the role of the immune system in adverse pregnancy outcomes. In this review, we discuss our present understanding of the ‘immunity of pregnancy’ in the context of the response to cervical and placental infections and how these responses affect both the mother and the fetus. We discuss novel and challenging concepts that help explain the immunological aspects of pregnancy and how the mother and fetus respond to infection.