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Recurrent cutaneous necrotising eosinophilic vasculitis
Author(s) -
Lin TengLi,
Yang ChiShun,
Chen YiJu
Publication year - 2021
Publication title -
australasian journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.67
H-Index - 53
eISSN - 1440-0960
pISSN - 0004-8380
DOI - 10.1111/ajd.13451
Subject(s) - medicine , vasculitis , eosinophilia , pathology , eosinophilic , differential diagnosis , dermatology , vascular disease , plexus , disease , surgery
Recurrent cutaneous necrotising eosinophilic vasculitis (RCNEV) is a rare disease that was first described in 1994. We report a case of RCNEV treated with corticosteroid, and 18 cases that we identified in the literature. Our review of the literature shows that RCNEV was frequently identified in middle‐aged females from Asia and usually presents as erythematous to purpuric papuloplaques, angio‐oedema on the extremities, as well as peripheral eosinophilia. Histopathologically, RCNEV is characterised by exclusively eosinophilic infiltration around the vascular plexus, the absence of leukocytoclasis and fibrinoid degeneration of vascular walls. Although, RCNEV responds to corticosteroid treatment, relapses have occurred during dose tapering. We also discuss the mechanisms of vascular destruction, the differential diagnosis and steroid‐sparing therapies for RCNEV.

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