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Re‐pigmentation of hair after prolonged cholinesterase inhibitor therapy in a Chinese population
Author(s) -
Chan Luke Kar Man,
Braidy Nady,
Ng Wyatt,
Xu Ying Hua,
Chen Jack,
McDonald Robert,
Chan Daniel Kam Yin
Publication year - 2020
Publication title -
australasian journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.67
H-Index - 53
eISSN - 1440-0960
pISSN - 0004-8380
DOI - 10.1111/ajd.13356
Subject(s) - medicine , cholinesterase , cabello , melanin , hair loss , dermatology , hair analysis , significant difference , population , physiology , pathology , scalp , alternative medicine , environmental health , biology , genetics
Eighty consecutive Chinese patients diagnosed with Alzheimer disease were assessed for darkening of grey hair. Of the 62 eligible patients (mean age = 79.3 ± 7.9 years; male: female = 1:1.48), 24/62 (38.7%, 95%CI: 26.6 – 51.9) reported hair darkening after prolonged usage of cholinesterase inhibitor for at least 6 months. Of the 24 patients with hair darkening, 17 (70.9%) experienced hair darkening in the occipital region, 3 (12.5%) in the parietal region, 2 (8.3%) patients in the frontal region and 2 (8.3%) patients experienced hair darkening in multiple regions. Analysis of melanin concentration showed no significant difference between darkened hair of patients after prolonged drug use and the dark hair of controls ( P = 0.381).
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