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A case of cutaneous extranodal natural killer/T‐cell lymphoma clinically and histopathologically mimicking interface dermatitis
Author(s) -
Choi Myoung Eun,
Yang Hee Joo,
Lee Woo Jin,
Won Chong Hyun,
Chang Sung Eun,
Choi Jee Ho,
Lee Mi Woo
Publication year - 2020
Publication title -
australasian journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.67
H-Index - 53
eISSN - 1440-0960
pISSN - 0004-8380
DOI - 10.1111/ajd.13304
Subject(s) - medicine , mycosis fungoides , lymphoma , infiltration (hvac) , pathology , t cell lymphoma , differential diagnosis , natural killer cell , natural killer t cell , cytotoxic t cell , t cell , immunology , immune system , biology , biochemistry , physics , in vitro , thermodynamics
Extranodal natural killer/T‐cell lymphoma (ENKTL) is a rare but aggressive cancer characterised by angiocentric and angiodestructive infiltration by NK‐cells, or cytotoxic T‐cell types. Histopathologically, ENKTL shows a multinodular or diffuse infiltration localised to vascular structures, resulting in angiodestruction and necrosis. We present a patient with an initially suspected diagnosis of benign interface dermatitis with a differential diagnosis of mycosis fungoides that was later found to be an aggressive extranodal natural killer/T‐cell lymphoma of a nasal type and with a dismal prognosis.