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An instructive case of amlodipine‐induced reversible granulomatous CD30 + T‐cell pseudolymphoma
Author(s) -
Cheong Kah Wai,
Lim Gareth Zigui,
Tan Kong Bing,
Lim Joel HuaLiang
Publication year - 2020
Publication title -
australasian journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.67
H-Index - 53
eISSN - 1440-0960
pISSN - 0004-8380
DOI - 10.1111/ajd.13240
Subject(s) - medicine , pseudolymphoma , histiocyte , pathology , histopathology , cd30 , amlodipine , immunohistochemistry , lymphoma , blood pressure
Abstract We report an unusual case of drug‐associated granulomatous CD30 + T‐cell pseudolymphoma secondary to amlodipine. A 55‐year‐old Chinese man presented with a 6‐month eruption of disseminated erythematous dermal papulonodules and annular infiltrated plaques over his neck and limbs symmetrically. Histopathology revealed a perivascular and interstitial infiltrate of histiocytes, eosinophils and morphologically normal lymphocytes associated with CD30 expression. The eruption improved rapidly after discontinuation of amlodipine and did not recur.