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Atypical severe progressive perioral ulceration due to herpes simplex virus on the background of undiagnosed HIV / AIDS
Author(s) -
Howard Matthew David,
Poon Flora,
Milne Olivia Jean,
Kelmann Anthony,
Chong Alvin H
Publication year - 2020
Publication title -
australasian journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.67
H-Index - 53
eISSN - 1440-0960
pISSN - 0004-8380
DOI - 10.1111/ajd.13111
Subject(s) - mucocutaneous zone , medicine , herpes simplex virus , dermatology , human immunodeficiency virus (hiv) , immunology , viral disease , chronic mucocutaneous candidiasis , immunopathology , virus , disease , pathology
Perioral ulcerative plaques have a broad list of differential diagnoses. We describe an unusual presentation of chronic progressive perioral ulceration due to herpes simplex type (HSV)‐1 on a background of undiagnosed human immunodeficiency virus infection with acquired immunodeficiency syndrome. Whilst chronic mucocutaneous HSV is an AIDS ‐defining condition with both HSV ‐1 and HSV ‐2 implicated, typical reported cases describe vesicular eruptions rather than perioral ulcerative plaques. This case highlights that common infections may present atypically in immunocompromised individuals and may be a clue to underlying systemic illness.