Premium
Cytomegalovirus ulcers following radiotherapy for a Marjolin ulcer in a renal transplant recipient
Author(s) -
Wang Charlie Y,
Mulley William R,
Dendle Claire,
Mar Adrian
Publication year - 2019
Publication title -
australasian journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.67
H-Index - 53
eISSN - 1440-0960
pISSN - 0004-8380
DOI - 10.1111/ajd.12921
Subject(s) - medicine , cytomegalovirus , renal transplant , radiation therapy , adjuvant radiotherapy , cytomegalovirus infection , transplantation , dermatology , surgery , kidney transplantation , virus , herpesviridae , viral disease , human cytomegalovirus , immunology
Cytomegalovirus ( CMV ) infection represents a major cause of morbidity and mortality in immunocompromised hosts. Skin ulceration is a rare manifestation of tissue‐invasive disease, with the anogenital region being the most typical site of involvement. We present a case of CMV ulceration on the right leg occurring 16 years following renal transplantation and 1 year after adjuvant radiotherapy for a Marjolin ulcer at this site. We suggest radiotherapy may provide a mechanism for local reactivation of the virus in the skin of seropositive patients.