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Transient acantholytic dyskeratosis (Grover's disease) after bone marrow transplantation
Author(s) -
Lim Penny Poh Lu,
Fernandez Penas Pablo,
Gottlieb David
Publication year - 2016
Publication title -
australasian journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.67
H-Index - 53
eISSN - 1440-0960
pISSN - 0004-8380
DOI - 10.1111/ajd.12517
Subject(s) - medicine , immunosuppression , disease , dyskeratosis congenita , dermatology , bone marrow transplantation , transplantation , dyskeratosis , hematopoietic stem cell transplantation , pathology , bone marrow , immunology , surgery , hyperkeratosis , dna , telomere , biology , genetics
Abstract Cutaneous eruptions in recipients of allogeneic haematopoietic stem cell transplantation ( AHSCT ) are frequent, and common aetiologies include graft‐versus‐host disease ( GVHD ), drug reactions, viral infections and engraftment syndrome. Transient acantholytic dermatosis or Grover's disease has been described in oncology patients and it is rarely reported after AHSCT . However, this benign and self‐limiting condition should be histologically distinguished from other, more serious entities, mainly stage IV GVHD , in order to avoid inappropriate treatment with corticosteroids and intensive immunosuppression.
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