Premium
Treatment of nodular vasculitis with colchicine
Author(s) -
Wee Edmund,
Kelly Robert I
Publication year - 2017
Publication title -
australasian journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.67
H-Index - 53
eISSN - 1440-0960
pISSN - 0004-8380
DOI - 10.1111/ajd.12494
Subject(s) - medicine , colchicine , vasculitis , dermatology , panniculitis , refractory (planetary science) , tuberculosis , disease , surgery , pathology , physics , astrobiology
Nodular vasculitis (NV) refers to a chronic relapsing lobular panniculitis that is thought to be a hypersensitivity reaction to antigenic triggers. While it is commonly associated with tuberculosis, in many cases no underlying cause is found and the condition is difficult to manage. Here, we report three patients with refractory idiopathic NV effectively treated with colchicine, leading to a significant improvement or complete resolution of their symptoms. Colchicine was successfully used as a steroid‐sparing agent, and in one patient its cessation was associated with a flare of disease.