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The spontaneous regression of palmoplantar pustulosis following removal of dental amalgams: A report of two cases
Author(s) -
Liu Fang,
Zhang Min,
Lou Yanfeng,
Liu Haibo,
Sang Hong
Publication year - 2016
Publication title -
australasian journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.67
H-Index - 53
eISSN - 1440-0960
pISSN - 0004-8380
DOI - 10.1111/ajd.12366
Subject(s) - palmoplantar pustulosis , medicine , cobalt chloride , dermatology , pustulosis , patch test , psoriasis , dentistry , cobalt , immunology , allergy , synovitis , inorganic chemistry , chemistry , arthritis
Metal allergens are occasionally reported to be associated with palmoplantar pustulosis. We describe two severe, therapy‐resistant, chronic cases of palmoplantar pustulosis induced by metal dental fillings. Both patients' clinical findings and symptoms regressed following the removal of their metal teeth. A patch test examination revealed positive reactions to metal allergens in both cases (in C ase 1 the positive reactions were to cobalt chloride hexahydrate and nickel sulfate and in C ase 2 the positive reaction was to nickel sulphate). Our studies suggest that metal allergens may play an important role in the pathogenesis of palmoplantar pustulosis.