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Evaluation of insulin resistance in idiopathic hirsutism compared with polycystic ovary syndrome patients and healthy individuals
Author(s) -
Bonakdaran Shokoufeh,
Kiafar Bita,
Barazandeh Ahmadabadi Fatemeh
Publication year - 2016
Publication title -
australasian journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.67
H-Index - 53
eISSN - 1440-0960
pISSN - 0004-8380
DOI - 10.1111/ajd.12276
Subject(s) - hirsutism , medicine , insulin resistance , polycystic ovary , endocrinology , insulin
Hirsutism is defined as the excessive male‐pattern growth of hair in women. Hirsutism is often idiopathic or the consequence of polycystic ovary syndrome ( PCOS ). Insulin resistance is common in PCOS (especially in obese patients) but the association between insulin resistance and idiopathic hirsutism ( IH ) is not clear. The aim of this study was to investigate the rate of insulin resistance in IH , compared with healthy individuals and patients with PCOS . Methods The study included three groups, patients with idiopathic hirsutism, PCOS and healthy women. Each group included 30 non‐obese women. Fasting blood sugar ( FBS ), insulin level and insulin resistance (estimated by the homeostasis model assessment [ HOMA ‐ IRIR ]) were compared in the three groups. Results There was a significant difference between the age of the women with IH compared with two other groups. There were no significant difference in levels of serum insulin ( P = 0.49, HOMA ‐ IR ( P = 0.47) and prevalence of insulin resistance ( P = 0.07) in the three groups. The age‐adjusted prevalence of insulin resistance was similar in the three groups. Conclusion Insulin resistance was no more frequent in IH patients than in healthy control groups.