Dermoscopy, reflectance confocal microscopy and histopathology of a melanoma  in situ  from an individual homozygous for  GSTP 1*105 V al/ MC 1 R *92 M et | Zendy

Banan Parastoo | Zendy; Lee Katie J | Zendy; McClenahan Phil | Zendy; Jagirdar Kasturee | Zendy; Sturm Richard A | Zendy; Soyer H Peter | Zendy

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Dermoscopy, reflectance confocal microscopy and histopathology of a melanoma in situ from an individual homozygous for GSTP 1*105 V al/ MC 1 R *92 M et

Author(s) -

Banan Parastoo,

Lee Katie J,

McClenahan Phil,

Jagirdar Kasturee,

Sturm Richard A,

Soyer H Peter

Publication year - 2016

Publication title -

australasian journal of dermatology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.67

H-Index - 53

eISSN - 1440-0960

pISSN - 0004-8380

DOI - 10.1111/ajd.12250

Subject(s) - histopathology , melanoma , medicine , confocal microscopy , glutathione , pathology , in situ , microbiology and biotechnology , enzyme , cancer research , biology , chemistry , biochemistry , organic chemistry

Glutathione S ‐transferase 1 is an enzyme involved in the detoxification of reactive oxygen species, and the rs1695* V al polymorphism has been proposed as a melanoma‐associated variant with significant effect. We report a case of malignant melanoma in an individual homozygous for the rs1695* V al variant and discuss the non‐invasive and histopathological tools used in diagnosis.

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