Nicotinamide and the skin | Zendy

Chen Andrew C | Zendy; Damian Diona L | Zendy

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Nicotinamide and the skin

Author(s) -

Chen Andrew C,

Damian Diona L

Publication year - 2014

Publication title -

australasian journal of dermatology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.67

H-Index - 53

eISSN - 1440-0960

pISSN - 0004-8380

DOI - 10.1111/ajd.12163

Subject(s) - nicotinamide , medicine , rosacea , atopic dermatitis , acne , niacinamide , dermatology , psoriasis , skin cancer , cancer research , enzyme , biochemistry , cancer , biology

Nicotinamide, an amide form of vitamin B3 , boosts cellular energy and regulates poly‐ ADP ‐ribose‐polymerase 1, an enzyme with important roles in DNA repair and the expression of inflammatory cytokines. Nicotinamide shows promise for the treatment of a wide range of dermatological conditions, including autoimmune blistering disorders, acne, rosacea, ageing skin and atopic dermatitis. In particular, recent studies have also shown it to be a potential agent for reducing actinic keratoses and preventing skin cancers.

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