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Cerebral vasculitis and multi‐focal neurological deficits due to allopurinol‐induced hypersensitivity syndrome
Author(s) -
Lim David,
Rademaker Marius,
Asztely Fredrik,
Ratnaweera Manjula,
Coltman Glenn
Publication year - 2014
Publication title -
australasian journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.67
H-Index - 53
eISSN - 1440-0960
pISSN - 0004-8380
DOI - 10.1111/ajd.12016
Subject(s) - medicine , allopurinol , vasculitis , cerebral vasculitis , magnetic resonance imaging , dermatology , pathology , radiology , disease
Drug‐induced hypersensitivity syndrome ( DIHS ) is a multi‐system syndrome resulting from an idiosyncratic reaction to medication. While it commonly results in multi‐organ involvement, particularly the liver, there are few reports of DIHS causing cerebral vasculitis and neurological deficits. We report the case of a 63‐year old woman with DIHS secondary to allopurinol leading to multiple neurological deficits with magnetic resonance imaging findings consistent with a cerebral vasculitis.