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Early phase oncology clinical trials in Malaysia: current status and future perspectives
Author(s) -
Voon PeiJye,
Lai WeiHong,
Bustaman Ros Suzanna,
Siu Lillian L.,
Razak Albiruni R. Abdul,
Yusof Akhmal,
Abdullah Noor Hisham
Publication year - 2023
Publication title -
asia‐pacific journal of clinical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.73
H-Index - 29
eISSN - 1743-7563
pISSN - 1743-7555
DOI - 10.1111/ajco.13886
Subject(s) - clinical trial , drug development , facilitator , government (linguistics) , enabling , clinical oncology , medicine , oncology , political science , business , economic growth , pharmacology , drug , cancer , linguistics , philosophy , psychiatry , law , economics
Historically, the majority of oncology clinical trials are conducted in Western Europe and North America. Globalization of drug development has resulted in sponsors shifting their focus to the Asia‐Pacific region. In Malaysia, implementation of various government policies to promote clinical trials has been initiated over a decade ago and includes the establishment of Clinical Research Malaysia, which functions as a facilitator and enabler of industry‐sponsored clinical trials on a nationwide basis. Although oncology clinical trials in Malaysia have seen promising growth, there are still only a limited number of early phase oncology studies being conducted. Hence, the Phase 1 Realization Project was initiated to develop Malaysia's early phase clinical trial capabilities. In addition, the adaptation of good practices from other countries contribute to the effective implementation of existing initiatives to drive progress in the development of early phase drug development set up in Malaysia. Furthermore, holistic approaches with emphasis in training and education, infrastructure capacities, strategic alliances, reinforcement of upstream activities in the value chain of drug development, enhanced patient advocacy, coupled with continued commitment from policy makers are imperative in nurturing a resilient clinical research ecosystem in Malaysia.