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Diagnosis and surgical treatment of mediastinal solitary fibrous tumor
Author(s) -
Zhang Lei,
Liu Xuegang,
Li Xiaojun,
Tang Zhen,
Shi Chao,
Wang Gengming
Publication year - 2017
Publication title -
asia‐pacific journal of clinical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.73
H-Index - 29
eISSN - 1743-7563
pISSN - 1743-7555
DOI - 10.1111/ajco.12594
Subject(s) - medicine , pathological , mediastinal tumor , radiology , surgery , immunohistochemistry , radiation therapy , chest pain , metastasis , mediastinum , cancer
Aim The aim of this study was to investigate the clinical features as well as the diagnosis and treatment methods for mediastinal solitary fibrous tumor (MSFT). Methods The clinical data of 13 patients treated for pathologically confirmed MSFT were retrospectively analyzed. The clinical symptoms were mainly cough, chest tightness, chest pain and chest discomfort. It was difficult to distinguish MSFT from other types of tumors simply via imaging results, hence, the confirmative diagnosis required pathological and immunohistochemistry analysis. Results The tumors were completely resected for all patients. All patients were discharged after surgery and followed up for 2–85 months. One patient died of cerebral hemorrhage 2 months after the surgery, and the rest of the patients experienced no recurrence or metastasis during the follow‐up period. Conclusions MSFT is a rare type of mediastinal tumor, and the diagnosis requires pathological and immunohistochemical analysis. Surgical treatment is preferred, and a complete resection can achieve a good prognosis; however, postoperative adjuvant radiotherapy might be necessary for cases with extensive external invasion.