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Positive sentinel lymph node metastasis from a metastasis in M elanoma
Author(s) -
Bowyer Samantha,
Feeney Kynan,
Millward Michael
Publication year - 2014
Publication title -
asia‐pacific journal of clinical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.73
H-Index - 29
eISSN - 1743-7563
pISSN - 1743-7555
DOI - 10.1111/ajco.12169
Subject(s) - medicine , melanoma , metastasis , sentinel lymph node , disease , metastatic melanoma , oncology , lymph , lymph node , breast cancer , primary tumor , lymph node metastasis , pathology , cancer , cancer research
The rationale for certain patterns of metastatic spread seen in melanoma is not well understood. Currently, there is no clear experimental evidence to support the potential for metastases to form metastases in this disease. We report a case of a 31‐year‐old woman, with metastatic melanoma, who developed axillary lymph node metastases hypothesized to originate from a breast metastasis rather than the primary disease. Improved understanding of the underlying molecular processes involved in systemic spread would facilitate development of improved adjuvant therapies and prognostic markers.