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Cranofacial osteosarcoma: Single institutional experience in K orea
Author(s) -
Lim Seungtaek,
Lee Soohyeon,
Rha Sun Young,
Rho Jae Kyung
Publication year - 2016
Publication title -
asia‐pacific journal of clinical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.73
H-Index - 29
eISSN - 1743-7563
pISSN - 1743-7555
DOI - 10.1111/ajco.12072
Subject(s) - medicine , metastasectomy , osteosarcoma , craniofacial , surgery , head and neck , overall survival , disease , cancer , metastasis , pathology , psychiatry
Craniofacial osteosarcoma is a rare disease accounting for only 1% of all head and neck malignancies. Its clinical features and optimal treatments are not yet clearly established. Methods We retrospectively analyzed the clinical course of 15 patients with craniofacial osteosarcoma treated in a single institute. Results Out of 13 patients who initially underwent primary mass resection, disease recurrence was found in five (36%). Patients with positive surgical margins showed higher recurrence and shorter median recurrence‐free and overall survival. Of three patients who had secondary operation after local recurrence, two survived for 44.6 and 64.2 months, respectively. One patient who underwent repeated lung metastasectomy had a disease‐free survival of 18.4 months from the first recurrence. Conclusion The current study demonstrates that positive surgical margins are important predictive factors for recurrence and overall survival. Salvage surgery for local recurrence and metastasectomy for systemic recurrence might have a positive impact on survival.