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Necrolytic migratory erythema associated with glucagonoma syndrome diagnosed by 68 Ga ‐ DOTANOC PET ‐ CT
Author(s) -
Sahoo Manas K,
Gupta Somesh,
Singh Ishita,
Pahwa Shivani,
Durgapal Prashant,
Bal Chandra Sekhar
Publication year - 2014
Publication title -
asia‐pacific journal of clinical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.73
H-Index - 29
eISSN - 1743-7563
pISSN - 1743-7555
DOI - 10.1111/ajco.12048
Subject(s) - glucagonoma , medicine , positron emission tomography , pancreas , radiology , positron emission tomography computed tomography , metastasis , erythema , nuclear medicine , computed tomography , cancer , dermatology , insulinoma
N ecrolytic migratory erythema ( NME ) is a rare dermatological condition which presents a diagnostic challenge. Repeated negative skin biopsies and non‐detection of any pancreatic tumor in conventional imaging modalities like a computed tomography ( CT) scan and ultrasonogram ( USG ) make the diagnosis more difficult. By the time the diagnosis is made, the patient usually presents with metastasis. We present a rare case of difficult to diagnose NME, as repeated skin biopsies and conventional imaging modalities like CT and USG could not detect the underlying glucagonoma. A 68 Ga ‐ DOTANOC positron emission tomography PET ‐ CT was able to detect the underlying cause of NME as glucagonoma of the pancreas and the same investigation confirmed the absence of any metastasis elsewhere in the body. The tumor was excised and patient dramatically improved, and all skin lesions disappeared.